罗秀菊
电子邮件:xjluo22@csu.edu.cn;xjluo2011@yahoo.com
个人简介
罗秀菊,女,教授,博士生导师,现为湘雅三医院检验科临床检验基础与血液学检验老师。
主要研究方向为心脑血管疾病(如脑卒中、心肌缺血等)、肿瘤的发病机制及分子诊断,已在国际权威和知名期刊发表SCI论文40余篇,其中第一或(并列)通讯作者SCI论文20余篇,授权专利3项,参编教材1部。获得中南大学西南铝及比亚迪奖励金“优秀教师奖”、Research Assistant Scholarship(美国Washington State University)等多项奖励;主持国家自然科学基金面上项目2项、湖南省自然科学基金面上项目1项、长沙市自然科学基金面上项目1项,参与重大研究计划培育项目、国家自然科学基金、教育部博士点基金和湖南省自然科学基金重点项目多项。
代表性论文 (*为通讯作者)
1. Tang LJ, Zhou YJ, Xiong XM, Li NS, Zhang JJ, Luo XJ*, Peng J*.Ubiquitin-specific protease 7 promotes ferroptosis via activation of the p53/TfR1 pathway in the rat hearts after ischemia/reperfusion.Free Radic Biol Med. 2021;162:339-352.
2. Lu LQ, Tian J, Luo XJ*, Peng J*. Targeting the pathways of regulated necrosis: a potential strategy for alleviation of cardio-cerebrovascular injury. Cell Mol Life Sci. 2021;78(1):63-78.
3. Jia MM, Li YQ, Xu KQ, Zhang YY, Tan SM, Zhang Q, Peng J, Luo XJ*. Jujuboside B promotes the death of acute leukemia cell in a RIPK1/RIPK3/MLKL pathway-dependent manner. Eur J Pharmacol. 2020;876:173041.
4. Ren KD, Liu WN, Tian J, Zhang YY, Peng JJ, Zhang D, Li NS, Yang J, Peng J, Luo XJ*.Mitochondrial E3 ubiquitin ligase 1 promotes brain injury by disturbing mitochondrial dynamics in a rat model of ischemic stroke. Eur J Pharmacol. 2019;861:172617.
5. Li YQ,Peng JJ, Peng J, Luo XJ*. The deafness gene GSDME: its involvement in cell apoptosis, secondary necrosis, and cancers. Naunyn Schmiedebergs Arch Pharmacol. 2019;392(9):1043-1048.
6. Zhang YY, Liu WN, Li YQ, Zhang XJ, Yang J, Luo XJ*, Peng J*. Ligustroflavone reduces necroptosis in rat brain after ischemic stroke through targeting RIPK1/RIPK3/MLKL pathway.Naunyn Schmiedebergs Arch Pharmacol. 2019;392(9): 1085-1095.
7. Guo S,Zhang YY, Peng JJ, Li YQ, Liu WN, Tang MX, Zhang XJ, Yang J, Peng J,Luo XJ*. Natural compound methyl protodioscin protects rat brain from ischemia/reperfusion injury through regulation of Mul1/SOD2 pathway. Eur J Pharmacol. 2019;849:50-58.
8. Tian J, Guo S, Chen H, Peng JJ, Jia MM, Li NS, Zhang XJ, Yang J,Luo XJ*, Peng J*. Combination of Emricasan with Ponatinib Synergistically Reduces Ischemia/Reperfusion Injury in Rat Brain Through Simultaneous Prevention of Apoptosis and Necroptosis.
Transl Stroke Res. 2018;9(4):382-392.
9. Li TB, Zhang YZ, Liu WQ, Zhang JJ, Peng J,Luo XJ*, Ma QL. Correlation between NADPH oxidase-mediated oxidative stress and dysfunction of endothelial progenitor cell in hyperlipidemic patients.Korean J Intern Med. Korean J Intern Med. 2018;33(2):313-322.
10. Zhang JJ, Liu WQ, Peng JJ, Ma QL, Peng J*,Luo XJ*.miR-21-5p/203a-3p promote ox-LDL-induced endothelial cell senescence through down-regulation of mitochondrial fission protein Drp1.Mech Ageing Dev. 2017;164:8-19
11. Li JH, Ju GX, Jiang JL, Li NS, Peng J,Luo XJ*. Lipoic acid protects gastric mucosa from ethanol-induced injury in rat through a mechanism involving aldehyde dehydrogenase 2 activation. Alcohol. 2016;56:21-28.
12. Yang ZB, Li TB, Zhang Z, Ren KD, Zheng ZF, Peng J,Luo XJ*. The Diagnostic Value of Circulating Brain-specific MicroRNAs for Ischemic Stroke. Intern Med. 2016;55(10):1279-86.