彭军,男,湖南长沙人。    

通讯地址:长沙市湘雅路110号，中南大学药学院药理学系，    

邮编410078    

Tel: 0731-82355080    

Email:junpeng@csu.edu.cnorjunpeng168@yahoo.com

 

任职情况：中南大学教授，博士生导师，升华学者特聘教授    

中南大学药学院药理学系副主任

中南大学药高血压病研究所药理研究室主任    

中国动脉硬化杂志编委，国际动脉硬化学会中国分会理事，    

中国动脉硬化专业委员会委员，    

国家自然科学基金项目评审专家。    

学习经历    

2002, 06 - 2007, 07,美国华盛顿州立大学博士后    

2002, 07,中南大学湘雅医学院药理学专业,医学博士学位    

1997, 7湖南医科大学生物化学和分子生物学专业,医学硕士学位.    

1991, 7湖南医科大学医学检验系,医学学士学位.    

工作经历    

2007.08 -至今，中南大学湘雅医学院药理学系，教授    

2003.01-2003. 05,德国柏林Max Delbruk Molecular Medicine Center，访问学者.    

1997, 7- 1999, 8 湖南医科大学生物化学教研室,助教,讲师    

1991, 7- 1994, 8 湖南医科大学临床生物化学教研室,助教    

 

科研基金项目    

1. 血管过氧化物酶介导的氧化应激促心肌重构的作用及机制 (国家自然科学基金, 2010-2012; No. 30971194,课题负责人:彭军, 31    

万人民币)    

2. TLR4介导的心肌缺血-再罐伤及CGRP的保护机制研究. (全国优博专项基金，2008.01－2009.12，2007B7课题负责人:彭军, 30万    

人民币)    

3. 心力衰竭与恶性心律失常的防治基础研究.(心衰与恶性心律失常与内源性保护分子网络关系的研究)（科技部973计划项目，    

2007-2011, 2007CB512007,本人为学术骨干,分配20万元课题经费）    

4. Target deletions in the mouse titin gene: role of PEVK and kinase domains. (美国心脏协会博士后基金; 2006-2008; No. 0620031Z,课题负    

责人:彭军, 14.5万美元)    

5. 吴茱萸碱和吴茱萸次碱诱导预适应及其分子机制. (国家自然科学基金, 2003-2005; No. 30200361,课题负责人:彭军, 22万人民币)    

 

主要奖励和荣誉    

入选湖南省121人才工程（2010年）    

入选湖南省高校学科带头人（2008年）    

获第六届湖南省青年科技奖（2007）    

获美国心脏协会Postdoctoral Fellowship (2006年)    

获全国优秀博士学位论文(2004年)    

获第五届复旦大学谈家桢基金九源奖学金二等奖(2002年)    

获首届中华医学科技进步二等奖(2001年)    

获湖南省科技进步二等奖(2001年)    

 

发表论文    

1. Li NS, Luo XJ,Dai Z, Liu B, Zhang YS, Yang ZC，Peng J(彭军,通讯作者). Beneficial effects of capsiate on ethanol-induced mucosal injury in rat are related to stimulation of calcitonin gene-related peptide release. Plant Med. 2011, in press.    

2. Luo XJ, Li NS, Zhang YS, Liu B, Yang ZC, Li YJ, Dong XR,Peng J(彭军,通讯作者). Vanillyl nonanoate protects rat gastric mucosa from ethanol-induced injury through a mechanism involving calcitonin gene-related peptide. Eur J Pharmacol. 2011 Sep;666(1-3):211-7.    

3. Shi R, Hu C, Yuan Q, Yang T,Peng J(彭军), Li Y, Bai Y, Cao Z, Cheng G, Zhang G. Involvement of vascular peroxide 1 in angiotensin II-induced vascular smooth muscle cell proliferation. Cardiovasc Res. 2011 Jul 1;91(1):27-36.    

4. Li TT, Zhang YS, He L, Li NS,Peng J(彭军), Li YJ. Protective effect of phloroglucinol against myocardial ischaemia-reperfusion injury is related to inhibition of myeloperoxidase activity and inflammatory cell infiltration. Clin Exp Pharmacol Physiol. 2011; 38: 27-33.    

5. Li JZ,Peng J(彭军，并列第一作者), Xiao L, Zhang YS, Liao MC, Li XH, Hu CP, Deng HW, Li YJ. Reversal of isoprenaline-induced cardiac remodeling by rutaecarpine via stimulation of calcitonin gene-related peptide production. Can J Physiol Pharmacol. 2010; 88(10):949-59.    

6. Luo XJ,Peng J(彭军), Li YJ. Recent advances in the study on capsaicinoids and capsinoids. Eur J Pharmacol. 2011; 650(1):1-7.    

7. Li NS, Luo XJ, Zhang YS, He L, Liu YZ,Peng J(彭军,通讯作者). Phloroglucinol protects gastric mucosa against ethanol-induced injury through regulating myeloperoxidase and catalase activities. Fundam Clin Pharmacol. 2011 Aug;25(4):462-8.    

8. Li XH,Peng J(彭军), Tan N, Wu WH, Li TT, Shi RZ, Li YJ. Involvement of asymmetric dimethylarginine and Rho kinase in the vascular remodeling in monocrotaline-induced pulmonary hypertension. Vascul Pharmacol. 2010; 53(5-6):223-9.    

9. Zhou Z, Hu CP, Wang CJ, Li TT,Peng J(彭军), Li YJ. Calcitonin gene-related peptide inhibits angiotensin II-induced endothelial progenitor cells senescence through up-regulation of klotho expression. Atherosclerosis. 2010; 213(1):92-101    

10. Li L, Luo XJ, Liu YZ, Zhang YS, Yuan Q, Tan N, Xiang DX,Peng J*(彭军，通讯作者).The role of the DDAH-ADMA pathway in the protective effect of resveratrol analog BTM-0512 on gastric mucosal injury. Can J Physiol Pharmacol. 2010 May;88(5):562-7.    

11. Zhou Z,Peng J (彭军), Wang CJ, Li D, Li TT, Hu CP, Chen XP, Li YJ. Accelerated senescence of endothelial progenitor cells in hypertension is related to the reduction of calcitonin gene-related peptide. J Hypertens. 2010 May;28(5):931-9    

12. Yuan Q,Peng J(彭军), Liu SY, Wang CJ, Xiang DX, Xiong XM, Hu CP, Li YJ. Inhibitory effect of resveratrol derivative BTM-0512 on high glucose-induced cell senescence involves dimethylaminohydrolase / asymmetric dimethylarginine pathway. Clin Exp Pharmacol Physiol. 2010 May;37(5-6): 630-5.    

13. Peng J(彭军), Li YJ. The vanilloid receptor TRPV1: role in cardiovascular and gastrointestinal protection. Eur J Pharmacol. 2010; 627(1-3):1-7.    

14. Lee EJ,Peng J(彭军), Radke M, Gotthardt M, Granzier HL. Calcium sensitivity and the Frank-Starling mechanism of the heart are increased in titin N2B region-deficient mice. J Mol Cell Cardiol. 2010; 49(3):449-58.    

15. Granzier HL*, Radke MH*,Peng J*(彭军，并列第一作者), Westermann D, Nelson OL, Rost K, King NM, Yu Q, Tschöpe C, McNabb M, Larson DF, Labeit S, Gotthardt M. Truncation of titin's elastic PEVK region leads to cardiomyopathy with diastolic dysfunction.Circ Res.2009; 105(6):557-64.

16. Zhang YM*,Peng J*(彭军，并列第一作者), Hu CP, Jiang QT, Jiang GL, Li YJ. Clonidine induces calcitonin gene-related peptide expression via nitric oxide pathway in endothelial cells.Peptides. 2009 Sep;30(9):1746-52.

17. Zhang XJ, Chang L, Zhang YM, Deng S, Li YJ,Peng J*(彭军，通讯作者). Comparing the role of glutathione -S- transferase and mitochondrial aldehyde dehydrogenase in nitroglycerin biotransformation and the correlation with calcitonin gene - related peptide. Eur J Pharmacol. 2009;617(1-3):97-101.    

18. Li D, Zhang XJ, Chen L, Yang ZC, Deng HW,Peng J * (彭军,通讯作者), Li YJ. Calcitonin gene-related peptide–mediated the cardioprotective effects of rutaecarpine on ischemia-reperfusion injury in spontaneous hypertensive rats. Clin Exp Pharmacol Physiol. 2009;36(7):662-7.    

19. Zhou Z, Hu CP, Wang CJ, Li TT,Peng J(彭军),Li YJ. Calcitonin gene-related peptide inhibits angiotensin II-induced endothelial progenitor cells senescence through up-regulation of klotho expression. Atherosclerosis. 2010; 213(1):92-101.    

20. Li D, Chen BM,Peng J(彭军),Zhang YS, Li XH, Yuan Q, Hu CP, Deng HW, Li YJ. Role of anandamide transporter in regulating calcitonin gene-related peptide production and blood pressure in hypertension. J Hypertens. 2009 Jun;27(6):1224-32.    

21. Peng J(彭军),Li YJ. New insights into nitroglycerin effects and tolerance: role of calcitonin gene - related peptide.European Journal of Pharmacology, 2008; 586 (1-3): 9 -13.

22. Huang XH, Li D, Li NS, Chen BM,Peng J(彭军), Li YJ. Cardioprotection afforded by norepinephrine-mediated postconditioning in isolated rat hearts.South ChinaJournal of Cardiology, 2008; 9(3):143-149.

23.Peng J(彭军), Raddatz K, Molkentin JD, Yiming Wu, Granzier H, Gotthardt M. Cardiac hypertrophy and reduced contractility in hearts deficient in titin kinase region.Circulation,2007, 115(6):743-51.(影响因子=11.632)

24. Radke MH,Peng J(彭军), Wu YM, McNabb M, Nelson OL, Granzier H, Gotthardt M. Targeted deletion of Titin’s N2B region leads to diastolic dysfunction and cardiac atrophy.Proc Natl Acad Sci USA,2007, 104(9): 3444-9 (影响因子=10.232).

25. Peng J(彭军), Raddatz K, Luo XJ, McNabb M, Yiming Wu, Granzier H, Gotthardt M. Impaired response to b-adrenergic stimulation in titin kinase deficient adult hearts.Biophysics J, 2006, 90: 2114-B462 (Abstract)(影响因子=4.507)

26.Peng J(彭军),Raddatz K, Labeit S, Granzier H, Gotthardt M.Muscle atrophy in titin M-line deficient mice,Journal of Muscle Research and Cell Motility, 2005; 26 (6-8): 381-8(影响因子=1.338).

27. Peng J (彭军), Lu R, Deng HW, Li Y. Involvement of alpha calcitonin gene-related peptide in monophosphoryl lipid A -induced delayed preconditioning in rat hearts.European Journal of Pharmacology, 2002; 436(1-2): 89-96 (影响因子= 2.477).

28. Peng J (彭军), Lu R, Deng HW, Li YJ.The heme oxygenase-1 pathway is involved in CGRP-mediated delayed preconditioning induced by monophosphoryl lipid A in rat hearts.Regulatory Peptides, 2002, 103 (1): 1-7(影响因子= 2.272).

29. Peng J (彭军), Xiao J, Ye F, Deng HW, Li YJ. Inhibition of cardiac TNF- alpha production by calcitonin gene-related peptide - mediated ischemic preconditioning in isolated rat hearts.European Journal of Pharmacology, 2000; 407; 303-308 (影响因子= 2.477).

30. Peng J (彭军), Lu R, Ye F, Deng HW, Li YJ. Induction of alpha calcitonin gene-related peptide mRNA expression in rat dorsal root ganglia by heat stress involves the heme oxygenase-1/carbon monoxide pathway.Neuropetides, 2001, 35(5-6):297-302(影响因子= 2.155).

31.Peng J (彭军), Lu R, Xiao L, Deng HW, Li YJ. Involvement of alpha calcitonin gene-related peptide in heat stress-induced delayed cardioprotection in rat hearts.Clinical Experimental Pharmacology and Physiology. 2002; 29(7): 569-74(影响因子= 1.437).

32. 彭军，鲁蓉，胡长平，李元建.热应激诱导大鼠心脏延迟保护作用及其机制.中南工业大学学报，2001；32：123-127.

33. 彭军,肖珺,李元建.降钙素基因相关肽的心血管保护作用.药理学进展,王永铭等主编. 2000; p128-134.

34. 彭军，李元建.创新：中国入世后新药研制的必由之路.湖南医科大学学报（社会科学版）2000; 2(1): 21-24.

35. 彭军，李元建. ATP敏感钾通道与心肌缺血预适应.中国药理学通报2000；16(2):141-144.

36. 曾卫民，彭军，万恂恂，陈淑华，宋惠萍.中国人2型糖尿病患者胰岛素受体底物-1基因变异的研究.中国糖尿病杂志，2000;8:75-77.

37. 张一帅，杨晶，彭军* (通讯作者),李元建,胡长平.神经元型一氧化氮合酶在心脏功能调节中的作用.中国药理学通报. 2009; 25(3):281-284.    

38. 张晓京，彭军*(通讯作者).有机硝酸酯的生物转化及其耐受机制的研究进展.中国药理学与毒理学杂志. 2009; 23 (4): 312-315.    

39. 何岚，彭军* (通讯作者).线粒体醛脱氢酶对心脏保护作用的研究进展.中国药理学通报.2009;25(12): 1548-1551.    

40. 李婷婷，彭军* (通讯作者).次氯酸介导的氧化应激及其病理生理学意义.中国药理学与毒理学杂. 2010,24(4): 307-310    

41. 谭娜，彭军* (通讯作者).非对称性二甲基精氨酸与肺动脉高.中国动脉硬化杂志.2009, 17(9): 790-793.    

42. 李健哲，邓汉武，彭军* (通讯作者).微小RNAs与心脏发育及疾病.国际病理科学与临床杂志. 2010, 30（2）：158-161.    

43. 彭军，陈小平，胡长平.八年制医学生药理学实验教学改革探索.医学教育探索. 2010, 9(5): 678-680