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罗秀菊副教授
2015-11-16 11:51 罗秀菊  医学检验系办公室 审核人:

罗秀菊

电子邮件:xjluo22@csu.edu.cn;xjluo2011@yahoo.com

个人简介

罗秀菊,女,副教授,病原生物学硕士、药理学博士,硕士生导师,现为湘雅医学院医学检验系临床检验基础与血液学检验老师。

主要研究方向为心脑血管疾病(如脑卒中、心肌缺血等)发病机制及分子诊断,已在国际权威和知名期刊发表SCI论文40余篇,其中第一或(并列)通讯作者SCI论文20余篇,参编教材1部。获得中南大学西南铝奖励金“优秀教师奖”、Research Assistant Scholarship(美国Washington State University)等多项奖励;主持国家自然科学基金和湖南省自然科学基金面上项目各1项,参与重大研究计划培育项目、国家自然科学基金、教育部博士点基金和湖南省自然科学基金重点项目多项。

代表性论文 (*为通讯作者)

1)Tian J, Guo S, Chen H, Peng JJ, Jia MM, Li NS, Zhang XJ, Yang J,Luo XJ*, Peng J*. Combination of Emricasan with Ponatinib Synergistically Reduces Ischemia/Reperfusion Injury in Rat Brain Through Simultaneous Prevention of Apoptosis and Necroptosis.Transl Stroke Res. 2018 Aug;9(4):382-392.

2)Li TB, Zhang YZ, Liu WQ, Zhang JJ, Peng J,Luo XJ*, Ma QL. Correlation between NADPH oxidase-mediated oxidative stress and dysfunction of endothelial progenitor cell in hyperlipidemic patients.Korean J Intern Med. Korean J Intern Med. 2018 Mar;33(2):313-322.

3)Zhang JJ, Liu WQ, Peng JJ, Ma QL, Peng J*,Luo XJ*.miR-21-5p/203a-3p promote ox-LDL-induced endothelial cell senescence through down-regulation of mitochondrial fission protein Drp1.Mech Ageing Dev. 2017 Jun;164:8-19

4)Li JH, Ju GX, Jiang JL, Li NS, Peng J,Luo XJ*. Lipoic acid protects gastric mucosa from ethanol-induced injury in rat through a mechanism involving aldehyde dehydrogenase 2 activation. Alcohol. 2016 Nov;56:21-28.

5)Yang ZB, Li TB, Zhang Z, Ren KD, Zheng ZF, Peng J,Luo XJ*. The Diagnostic Value of Circulating Brain-specific MicroRNAs for Ischemic Stroke. Intern Med. 2016;55(10):1279-86.

6)Peng J, Ren KD, Yang J,Luo XJ*. Mitochondrial E3 ubiquitin ligase 1: A key enzyme in regulation of mitochondrial dynamics and functions. Mitochondrion. 2016 ay;28:49-53.

7)Lou Z, Ren KD, Tan B, Peng JJ, Ren X, Yang ZB, Liu B, Yang J, Ma QL,Luo XJ*, Peng J*. Salviaolate Protects Rat Brain from Ischemia-Reperfusion Injury through Inhibition of NADPH Oxidase. Planta Med. 2015; 81(15):1361-9.

8)Zhang HF, Li TB, Liu B, Lou Z, Zhang JJ, Peng JJ, Zhang XJ, Ma QL, Peng J*,Luo XJ*.Inhibition of myosin light chain kinase reduces NADPH oxidase-mediated oxidative injury in rat brain following cerebral ischemia/reperfusion. Naunyn Schmiedebergs Arch Pharmacol. 2015;388(9):953-63.

9)Zhang YS, Liu B,Luo XJ,Zhang JJ, Li NS, Ma QL, Jiang JL, Li YJ, Li Q, Peng J.A novel function of nuclear non-muscle myosin regulatory light chain in promotion of xanthine oxidase transcription after myocardial ischemia/reperfusion.Free Radic Biol Med. 2015;83:115-28.

10)Zhang YS, Liu B,Luo XJ,, Li TB, Zhang JJ, Peng JJ, Zhang XJ, Ma QL, Hu CP, Li YJ, Peng J, Li Q. Nuclear cardiac myosin light chain 2 modulates NADPH oxidase 2 expression in myocardium: a novel function beyond muscle contraction. Basic Res Cardiol. 2015;110(4):38.

11)Yang ZB, Zhang Z, Li TB, Lou Z, Li SY, Yang H, Yang J,Luo XJ*, Peng J*. Upregulation of brain-enriched miR-107 promotes excitatory neurotoxicity through downregulation of glutamate transporter 1 expression following ischemic stroke. Clin Sci (Lond).2014;127(12): 679-89.

12)Yang ZB, Tan B, Li TB, Lou Z, Jiang JL, Zhou YJ, Yang J,Luo XJ*Peng J*. Protective effect of vitexin compound B-1 against hypoxia/reoxygenation -induced injury in differentiated PC12 cells via NADPH oxidase inhibition. Naunyn Schmiedebergs Arch Pharmacol. 2014 ;387(9):861-71.

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